Goals and objectives

This is the third international symposium on BA/BE of Oral Drug Products organized by the Bioavailability/Bioequivalence Focus Group in FIP's Special Interest Group on Regulatory Science. The first BA/BE symposium was held in Kobe, Japan, in 2011 and the second was in Seoul, Republic of Korea, in 2014. In both symposium, having leading professionals from all over the world as speakers, we could share the up-to-date information in the science of oral drug absorption, the strategy for oral drug development and the regulation for oral drug products.

This third symposium is held in Lisbon, Portugal, with the National Authority of Medicines and Health Products, I.P. (INFARMED, I.P.) as a co-sponsor. The main theme of the symposium "Biopharmaceutics meets Galenics" was chosen to emphasize the importance of integrating biopharmaceutical science into the development of oral drug formulations. With a right science in biopharmaceutics and an advanced technology for oral drug formulation, it is possible to maximize the therapeutic effects and minimize the patient's inconveniences to increase the Quality of Life.

The symposium consists of 5 sessions, starting with a session on in vitro methodology to predict BA/BE of oral drug products, then the second session introducing cutting-edge information on model and simulation of oral drug absorption. In the third session, fundamental theory and cutting-edge technology for oral formulations will be introduced. Forth session will focus on the innovative technology for oral drug delivery. Finally, current status of regulation of oral drug products in EU, USA, and Asia is presented to initiate the discussion on the international harmonization of oral drug regulation. Furthermore, we have one plenary lecture (from Prof. Gordon Amidon) and three special lectures relating to the topics of each session.

This symposium is held to encourage scientists and experts working in the filed of oral drug delivery and to promote the development of better drug products faster.

The final goals of this symposium are,

  • Understanding the up-to-date sciences in biopharmaceutic on oral drug absorption.
  • Understanding the methodology to integrate the science into the development of better oral formulations.
  • Understanding the cutting-edge technologies of oral drug delivery.
  • Understanding the current status of regulation for oral drug products in EU, USA and Asia to propose international standards for harmonization.

Main sponsors:

International Pharmaceutical Federation (FIP)

 

National Authority of Medicines and Health Products, I.P. (INFARMED)

 

 

Co-sponsors

The Academy of Pharmaceutical Science and Technology, Japan (APSTJ)

 

Drug Delivery Foundation (DDF)

 

Nagai Foundation, Tokyo

 

 

Co-chairs:

Gordon L. Amidon, Ph.D. (University of Michigan, USA)

José Morais, Ph.D. (University of Lisbon, Portugal)

Shinji Yamashita, Ph.D. (Setsunan University, Japan)

Organizing committee:

EU:        

Paulo Paixao Ph. D. (University of Lisbon, Portugal)

Marival Bermejo Ph. D. (Miguel Hernandez University, ES)

Patrick Augustijns, Ph. D. (The University of Leuven, Belgium)

US:

Yasuhiro Tsume, Ph.D (University of Michigan, USA)

Lynne Taylor (Purdue University, USA)

Xinyuan Zhang (FDA) former generic officer and do modeling/simulation

Asia/Oceania :

Kohsaku Kawakami Ph. D. (National Institute for Materials Science, Japan)

Kunikazu Moribe Ph.D. (University of Chiba, Japan)

Chris Porter Ph.D. (Monash University, Australia)

 

International advisory board:

Jennifer B. Dressman, Ph.D. (Goethe University, Germany)

Hans Lennernas, Ph.D. (Uppsala University, Sweden)

Peter Langguth, Ph.D. (University of Mainz, Germany)

Bertil Abrahamsson, Ph.D. (AstraZeneca, Sweden)

Ping Gao, Ph.D. (Abbott Laboratories, Inc., USA)

Lawrence Yu, Ph.D. (FDA, USA)

James Polli, Ph.D. (University of Maryland, USA)

Greg Amidon (University of Michigan, USA)

Mitsuru Hashida, Ph.D. (Kyoto University, Japan)

Tsuneji Nagai, Ph.D. (Nagai Foundation Tokyo, Japan)

Vincent H.L. Lee, Ph.D. (Chinese University of Hong Kong, Hong Kong)

Beom-Jin Lee, Ph.D. (Kangwon National University, Korea)

 

 

Local organizers:

Paulo Paixao Ph. D. (University of Lisbon, Portugal)

Nuno Silva Ph. D. (University of Lisbon, Portugal)

Luís Gouveia Ph. D. (University of Lisbon, Portugal)

Rosário Lobato Ph. D. (University of Lisbon, Portugal)

Important dates:

Registration start: May 1st, early registration until September 15th.

Abstract submission for poster presentation: July 15th

For prices and registration, the responsible entity is Drug Delivery Fundation. Please, register here!

   

Abstract submission for poster presenters

An Abstract must be prepared in English. Only one abstract as presenting author can be submitted. Names of presenting authors can be included as a co-author in other presentations.

Abstract must be prepared using the template. The template can be downloaded by clicking this URL.

Some abstracts will be selected for oral presentation. Publication of your paper in a special issue in the Journal of Drug Delivery Science and Technology is also encouraged.

Your abstract should be sent to Program office of BABE symposium by e-mail (babe2018@pharm.setsunan.ac.jp). A Word document format file is acceptable for the abstract. The file name should be "Last name-First name-affiliation". The abstract should be submitted before July 15th. We will send the e-mail about acceptance of your presentation by the end of September 15th. If you did not receive the acceptance e-mail, please contact to the office by e-mail.
 

Following information should be included in the e-mail when you submit the abstract:

1. Presenting (contact) author's name, affiliation, category (General/Student)

2. Presenting (contact) author's contact information (Address, telephone number, e-mail address etc.)

3. A topic of your abstract (Please select the number from the List of Topics).

4. Do you want to apply for oral presentation? (Yes/No)

If "Yes", your abstract is reviewed by BABE programing committee. If your paper is selected for the oral presentation, the time schedule of your oral presentation will be informed from the office of BABE symposium by July 31st.

5. Do you consider to submit for special issue in Journal of Drug Delivery Science and Technology? (Yes/No)

If "Yes", please consider that, if accepted, the submission period will go from Sept 1st to Nov 30th.

6. Estimated date for the registration payment.

Pre-registration is required for the poster presentation. Without the pre-registration, your poster presentation will be cancelled.

Guidelines for the poster presentation, for example, the maximum size allocated for each poster, will be informed later by e-mail.

If you need any assistance with poster submission, do not hesitate to contact with Program office of BABE symposium (babe2018@pharm.setsunan.ac.jp).


List of topics

1: In vivo performance of oral drug products - prediction from in vitro

2: Model and simulation of oral drug absorption

3: Formulation technologies accelerating drug discovery and development

4: Innovation in oral drug delivery

5: Other
 

Special issue in Journal of Drug Delivery Science and Technology

The poster that agreed to be submitted to the special issue (as a research paper) is considered for an oral presentation preferentially. Note that the paper will be published after standard peer review process.

Our Symposium will take place at the Auditorium on Tomé Pires building, at INFARMED, Autoridade Nacional do Medicamento e Produtos de Saúde ,I.P., in the Lisbon Health Park (Parque de Saúde de Lisboa)

Adress: Avenida do Brasil, 53 
1749 - 004 Lisboa.

GPS: 38°45'29.1"N 9°08'56.1"W

          38.758069, -9.148908


Our location

Lisbon Health Park is close to the Airport, to Campo Grande and to the Lisbon University.


You can drive by car (entering from the Rua das Murtas), by taxi or you can arrive by METRO (leaving at the Alvalade stop by using the Green Line) or BUS (Hospital Júlio de Matos Stop, by lines 206-717-731-735-750-755-767-783)

Finally, you should drive/walk to the Auditorium of Tomé Pires building inside the Lisbon Health Park

05-06-2018 - A special issue in the Journal of Drug Delivery Science and Technology for participants in the 3rd International Symposium on BA/BE of Oral Drug Products was accepted. All scientific works submitted to the Symposium are considered for publication after peer review process. The submission period is from Sep 1st to Nov 30th. For further details, please contact babe2018@pharm.setsunan.ac.jp.

About Portugal

Portugal is situated at the south-west point of Europe and also includes the Madeira and Azores archipelagos in the Atlantic Ocean. Just a few hours from any of the other European capitals and with its mild climate and splendid beaches bathed by the Atlantic Ocean, Portugal attracts visitors from all over the world.

This is a country that has the oldest borders in Europe, with several different landscapes just a short distance away, lots of leisure activities and a unique cultural heritage, where tradition and modernity blend together in perfect harmony. Its superb cuisine, fine wines and hospitable people make this a tourist paradise of the highest quality.

Portugal has something to interest everybody. It is steeped in history as the museums, palaces and castles show. There are plenty of places to shop and lively markets to explore. As for nightlife, there are enough discos, casinos and night-clubs to keep the most dedicated fun lover happy. For the outdoor types, there is every sport they could wish for, endless sun-kissed beaches, and plenty of swimming pools as well as golf courses.

The history of Portugal is unique in the European context. Pushed against the Atlantic Ocean, fighting for its independence along with other Iberian visigothic kingdoms, after the fall of the Roman Empire and following the conquering of most of the Iberian Peninsula by North African Muslims, Portugal initiated a saga that is considered the opening of Europe to new worlds and built an overseas empire by means of the famous Sea Discoveries led by Infante D. Henrique and his successors.

Photo by Nuno Silva

In order to keep its borders and independence Portugal fought numerous battles against, first the Moors, then its neighbours and later Napoleon himself in the 19th century. The new ideas arising from the French Revolution started a troubled 19th century, ending up in the Republican Revolution in 1910, starting the third Republic in Europe. A dictatorship led by Salazar was the main feature of the 20th century, which ended with the Carnation Revolution in April 1974. Since then, Portugal without its colonies thrived through the entrance into the European Union bringing in its multicontinental background. Financial problems arising from the recent world crisis are now being dealt with through the mechanisms of democracy and economic recovery.

Photo by Nuno Silva

About Lisboa

Lisboa is the capital of Portugal and lies on the north bank of the Tagus Estuary, on the European Atlantic coast. It is the westernmost city in continental Europe. Greater Lisboa has an area of approximately 1,000 km2. The city lies more or less in the centre of the country, approximately 300 km from the Algarve in the south and 400 km from the northern border with Spain.

Photo by Nuno Silva

The origins of Lisbon are shrouded in legend, among its mythical founders are Elisha and Ulysses. Its name derives from Olissapona, a Latin version of the Phoenician "Allis Ubbo" or "delightful little port".

Lisbon was occupied successively by Phoenicians around 1200 BC, followed by the Greeks, Carthaginians, Romans, Visigoths, Moors and finally conquered in 1147 AD by Portugal's first king, Afonso Henriques, with the aid of North European crusaders. The city was made Portugal's capital in 1255, and was the seat of the monarchy until the Republic in 1910.

As Portugal developed into the greatest power in the 15th century onwards, so Lisbon became a very important port, the centre for trade in spices and jewels from the East and gold from Brazil, and capital of the Portuguese Empire. The 1755 infamous earthquake, fire and tsunami destroyed most of the city, especially downtown by the Tagus waterfront. Marquis de Pombal was instrumental in rebuilding the city and initiating reforms that were the basis of modern Portugal.

Photo by Nuno Silva

Today, Lisbon is a lively, international city with a population of one and a half million, offering a fascinating combination of the old and the new, with an unmistakable character and a beauty all of its own. Lisboa offers a wide variety of options to the visitor, including beaches, countryside, mountains and areas of historical interest only a few kilometres away from the city centre.

For additional tourist information, please visit this link: http://www.planetware.com/tourist-attractions-/lisbon-p-lisb-lisb.htm

Getting to Lisbon

Lisbon is very easy to get to. It's just a short flight away from most European locations and also easily accessed by road, sea and rail.
Lisboa International Airport, 7 km from the city center, has daily flights to and from the major cities in Europe and the world. The Portuguese airline TAP - Air Portugal, as well as all major international Airlines and low cost companies, fly to and from Lisboa.

Lisbon Airport has direct bus and underground connections to the city centre. There are several inexpensive professional transport services available. Of course taxis are a fast way to reach the city centre and taxis are not expensive in Lisbon. They are lined up outside the terminals.

The Campus where the conference is located, is well served by several bus lines (206, 207, 701, 717, 731, 736, 750, 767, 783 and 798) and one Metro Station (Alvalade). There are several hotels within short distance.

Photo by Nuno Silva

Climate - Weather

Due to the influence of the Atlantic Ocean, Lisboa has a pleasant climate throughout the year. The agreeable temperatures in the summer months are an open invitation for a walk by the river, or to spend an afternoon in one of the many street cafés to be found all over the city. Although the temperatures may fall somewhat in the autumn and winter months, sunshine is almost always a constant feature.

Photo by Nuno Silva

Local time: Lisbon's time is in the WET - Western European Time zone (GMT/UTC GMT/UTC +1 in summer)

   

Need help? Questions? For conference-related topics, please email:

Europe / Africa

Paulo Paixão: ppaixao@ff.ulisboa.pt
 

North/South America

Gail Benninghoff: gben@med.umich.edu
 

Asia/Oceania

Shinji Yamashita: babe2018@pharm.setsunan.ac.jp
 

Symposium secretariat:

Secretariat of International Symposium on BA/BE of Oral Drug Products: secretariat.babe2018@gmail.com